As I Predicted, Gilead’s Sofosbuvir Likely To “Leapfrog” Merck’s MK-5172, In Hep C

28 04 2013

New Merck, Reviewed

More news is developing out of Amsterdam, at the EASL — as studies and papers are presented, as of Saturday night, European time. The upshot? These latest tea leaves suggest I was, indeed, right last week: Gilead looks to have the lead dog in the next gen Hep C space. One might even call it the full-on cure. But the study was actually too small to say that with a highly scientific degree of confidence.

But this does make the joint-BMS Daclatasvir combo with MK-5172 announcement look decidedly less exciting — as doctors are likely to go off label, and prescribe a homemade combo of Sofosbuvir and Daclatasvir, as soon as they are able. True, there could yet be an off-target effect problem — or some other glitch — but I now doubt that.

Do go read the Bloomberg piece, in total — but here’s a bit:

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One response

1 05 2013

Reblogged this on Organic Reactions in Medchem.

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